Following the deaths of 20 sheep in January this year and the successful rescue of a flock in September, floods struck the banks of the River Tame in Hopwas again on Sunday.
Firefighters from Tamworth were called to rescue the animals at 10.20am near Two Tree Close.
Approximately 100 sheep were stranded in flooded water near to the River Tame Bridge.
RSPCA officers and inspectors were also in attendance.
Shortly after crews left they were asked to return at 12.35pm due to reports that one of the sheep was tangled in brambles and had fallen into the river.
Despite working through the afternoon and successfully rescuing 80 sheep, around 20 of them drowned.
A spokeswoman for the RSPCA said: "The area has flooded before and it will flood again.
"The inspector has made a complaint to the council because this keeps happening. We can prosecute if we want to."